Clinical Brief: Implementation and Patient Support Strategies Main Discussion Topics: Role of multidisciplinary care team in patient education and support Importance of early intervention for side effect management Strategies for ensuring medication adherence with oral therapy Value of nurse coordinators […]
Clinical Brief: Real-World Evidence Supporting Elacestrant Use Main Discussion Topics: Real-world outcomes exceeding clinical trial results (unusual finding) GUARDIAN database analysis: 6.4 months median time to treatment failure Komoda database: 6.8 months progression-free survival (9.4 months if fulvestrant-naive) Expert clinical
The Efficacy and Tolerability of Oral Elacestrant for Patients with ESR1 Mutations Read More »
Clinical Brief: Elacestrant Subgroup Benefits and Safety Profile Main Discussion Topics: Efficacy across different disease sites (bone-only versus visceral) Impact of tumor burden (multiple sites of metastasis) Co-mutation status (PIK3CA, p53) and treatment efficacy Safety profile focusing on gastrointestinal (GI)
What Prior CDK4/6i Duration Means for Treatment Success Read More »
Clinical Brief: Second-Line Treatment Decision Framework Main Discussion Topics: Integration of patient factors in treatment selection Balance between efficacy and quality-of-life considerations Practical considerations: insurance, copays, administration route Sequential versus concurrent treatment strategies Role of shared decision-making in complex treatment
From Patient Selection to Supportive Care Read More »
